Oncology & Cancer

Combination therapy doubles survival in metastatic lung cancer

The immunotherapy drug pembrolizumab, when combined with chemotherapy, doubles survival in patients with non-squamous non-small cell lung cancer (NSNSCLC) lacking genetic changes in the EGFR or ALK genes, when compared to ...

Ophthalmology

Repeated ranibizumab doesn't impair macular perfusion

(HealthDay)—For patients with diabetic macular edema, repeated ranibizumab treatment does not appear to be associated with impaired macular perfusion, according to a study published online March 1 in JAMA Ophthalmology.

HIV & AIDS

Individuals with HIV at higher risk for heart disease

A review of more than 80 studies reveals that changes in the immune cells of people with human immunodeficiency virus (HIV) infection may increase their risk of cardiovascular disease (CVD). The review is published in the ...

Alzheimer's disease & dementia

Molecular mechanism behind HIV-associated dementia revealed

For the first time, scientists have identified and inhibited a molecular process that can lead to neurodegeneration in patients with HIV, according to a Northwestern Medicine study published in Nature Communications.

Immunology

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online Dec. 28 in PLOS Pathogens.

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