Addition of the integrase strand transfer inhibitor raltegravir (RAL) to standard antiretroviral therapy (ART) in ART-naive patients with early HIV infection was not associated with a difference in the quantity of HIV DNA, ...
Feb 22, 2016
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(Medical Xpress)—It's a good news/bad news scenario: Researchers have made a new discovery about HIV that will redirect curative strategies toward latent reservoirs of HIV—that's the good news. The bad news is that they ...
When metastatic tumors driven by drug-targetable genetic mutations become resistant to a targeted therapy drug, the usual practice is to biopsy a single metastatic lesion to test for new mutations that can guide the selection ...
Feb 5, 2016
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Dabrafenib (trade name: Tafinlar) has been approved since 2013 for the treatment of adults with advanced, i.e. metastatic or unresectable, melanoma with a BRAF V600 mutation. Since September 2015, dabrafenib has been approved ...
Jan 13, 2016
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Gene therapy can safely rebuild the immune systems of older children and young adults with X-linked severe combined immunodeficiency (SCID-X1), a rare inherited disorder that primarily affects males, scientists from the National ...
Dec 6, 2015
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Postmenopausal African American women who use female hormone supplements containing estrogen and progestin ("combination" therapy) are at an increased risk for estrogen receptor positive breast cancer.
Nov 30, 2015
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Among patients with peripheral artery disease and intermittent claudication (cramping pain in the legs due to poor circulation in the arteries, aggravated by walking), a combination therapy of endovascular revascularization ...
Nov 8, 2015
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Patients with advanced melanoma skin cancer survive for longer without their disease progressing if they have been treated with a combination of two drugs, nivolumab and ipilimumab, than with either of these drugs alone. ...
Sep 28, 2015
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Scientists have been exploring the connection between tricyclic antidepressants and brain cancer since the early 2000s. There's some evidence that the drugs can lower one's risk for developing aggressive glioblastomas, but ...
Sep 24, 2015
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Common diabetes drugs might help eradicate drug-resistant cancer cells in a certain form of leukemia when added to standard treatment, a small new study suggests.
Sep 2, 2015
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