Oncology & Cancer

Searching for therapeutic synergy in primary effusion lymphoma

Primary effusion lymphoma (PEL) is a rare, fatal form of aggressive B-cell lymphoma caused by Kaposi's sarcoma-associated herpesvirus (KSHV). The disease most commonly occurs in immunocompromised patients, such as those with ...

Diseases, Conditions, Syndromes

Resistance to combination drugs threatens efforts to eradicate malaria

With 300-500 million people falling ill to malaria each year, this debilitating tropical disease remains a global problem. Current combination drug therapy is still generally effective, but recent signs of resistance present ...

Oncology & Cancer

New data on combination treatments for melanoma

Combination therapy with both BRAF inhibitor vemurafenib and MEK inhibitor cobimetinib achieves greater progression-free survival and response rates than vemurafenib plus placebo in BRAF-mutation positive melanoma, according ...

Diseases, Conditions, Syndromes

Combination therapy cures tick-borne illness in mice

A novel combination therapy cures an emerging infectious disease, babesiosis, which is transmitted by the same ticks that transmit the agents of Lyme disease, said Yale researchers. This "radical" therapy not only clears ...

Medications

Ramucirumab in stomach cancer: Added benefit not proven

Ramucirumab (trade name: Cyramza) is a monoclonal antibody, which blocks a receptor, reducing the growth of blood vessels and so reducing blood supply to the tumours. This aims to slow the growth of the tumours. As a so-called ...

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