The largest genetic search for "obesity genes" in people of African ancestry has led to the discovery of three new regions of the human genome that influence obesity in these populations and others.
Apr 15, 2013
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Columbia University Medical Center (CUMC) researchers have discovered a common genetic variant that greatly impacts normal brain aging, starting at around age 65, and may modify the risk for neurodegenerative diseases. The ...
Mar 15, 2017
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Personalized medicine—where the proper medicine and proper dose are used for the individual patient—moved a step closer to reality for children suffering from eosinophilic esophagitis (EoE), an inflammation of the food ...
Sep 12, 2019
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A pair of studies by researchers at UC San Francisco suggest that genetic variants that have distinct effects on physical traits such as height, weight, body mass, and body shape in men versus women are also linked to men's ...
Jan 23, 2017
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The human organism requires a variety of small molecules, such as sugars or fats, in order to function properly. The composition of these so-called metabolites and their interaction—the metabolism—varies from person to ...
Jan 13, 2021
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Recent breakthroughs in the analysis of genetic variation in large populations have led to the discovery of hundreds of genes involved in dozens of common diseases. Many of these discoveries were enabled by performing "meta-analysis," ...
May 17, 2011
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Genetic discoveries over the past 25 years have substantially advanced understanding of both rare and common diseases, furthering the development of treatment and prevention for ailments ranging from inflammatory bowel diseases ...
Jan 27, 2020
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A common antibacterial substance found in toothpaste may combat life-threatening diseases such as cystic fibrosis, or CF, when combined with an already FDA-approved drug.
May 17, 2018
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Gene scans for everyone? Not so fast. New research suggests that for the average person, decoding your own DNA may not turn out to be a really useful crystal ball for future health.
Apr 2, 2012
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Although some rare genetic variants can increase the risk of disease markedly for a few individuals, the genetic contribution to common diseases is mostly due to a combination of many common genetic variants with small effects. ...
May 16, 2022
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