Tyrosine kinase inhibitors (TKIs) kill cancerous cells by inducing programmed cell death. They are of enormous therapeutic benefit to patients with chronic myeloid leukemia (CML) and certain types of lung cancer, but their ...
Aug 2, 2012
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One-letter switches in the DNA code occur much more frequently in human genomes than anticipated, but are often only found in one or a few individuals.
May 17, 2012
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(Medical Xpress) -- Since 2005, genome-wide association studies (GWAS) have successfully identified thousands of genes responsible for common human diseases.
Jan 13, 2012
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Although the U.S. Food and Drug Administration (FDA) has recommended that a certain type of genetic testing (for the genotype CYP2C19) be considered before prescribing the drug clopidogrel to identify individuals who may ...
Dec 27, 2011
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Asthma patients could clearly benefit from personalized medicine, a new study suggests. However, the new discovery of a key gene, while exciting, does not mean that day is here quite yet.
Oct 5, 2011
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Scientists at Helmholtz Zentrum Munich and LMU Munich, in cooperation with Wellcome Trust Sanger Institute and King's College London (KCL), have identified several associations between genetic variants and specific metabolic ...
Sep 1, 2011
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Researchers have undertaken the most comprehensive investigation of genetic variance in human metabolism and discovered new insights into a range of common diseases. Their work has revealed 37 new variants that are associated ...
Aug 31, 2011
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Recent breakthroughs in the analysis of genetic variation in large populations have led to the discovery of hundreds of genes involved in dozens of common diseases. Many of these discoveries were enabled by performing "meta-analysis," ...
May 17, 2011
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