Medications

Drug interaction causes hypotension

The commonly used muscle relaxant tizanidine can lower blood pressure. Tizanidine is metabolized by the enzyme CYP1A2, and concurrent use of tizanidine and a CYP1A2 inhibitor, such as ciprofloxacin, greatly increases tizanidine ...

Oncology & Cancer

Risk factors ID'd for diffuse large B-cell lymphoma mortality

(HealthDay)—Age, stage, and Charlson Comorbidity Index (CCI) are risk factors for diffuse large B-cell lymphoma (DLBCL)-specific death in older patients, according to a study published online Feb. 1 in Cancer.

Medications

Odds of death up with exposure to pregabalin, opioids

(HealthDay)—Concomitant exposure to pregabalin and opioids is associated with increased odds of opioid-related death, according to a research letter published online Aug. 21 in the Annals of Internal Medicine.

Arthritis & Rheumatism

Obesity may worsen symptoms for patients with lupus

In a recent Arthritis Care & Research study of 148 women with lupus, obesity was linked with worse disease activity, depressive symptoms, and symptoms of pain and fatigue. The association was consistent across different definitions ...

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