Inflammatory disorders

Effective treatments for urticarial vasculitis

What treatments are available for patients with the rare inflammatory disease known as urticarial vasculitis? How effective are these treatments? Researchers from Charité - Universitätsmedizin Berlin embarked on a systematic ...

Medical research

Complex diseases get the big data treatment

The big data explosion, which allows scientists to analyse factors such as people's lifestyles, genes and medical records to develop personalised treatments for conditions, has so far mostly benefitted rare diseases with ...

Diseases, Conditions, Syndromes

Drug to treat skin lesions in rare tuberous sclerosis complex approved

Scientists at Osaka University developed a new drug treating skin lesions in tuberous sclerosis complex (TSC), a rare intractable disease, a world first. Following the physician-led clinical studies I and II by Osaka University, ...

Genetics

What are mitochondria and how did we come to have them?

We've probably all heard of mitochondria, and we may even remember learning in school that they are the "powerhouses of the cell" – but what does that actually mean, and how did they evolve? To answer this question, we ...

Medical research

Microbial cooperation in the intestine

The human intestine is home to a dense and diverse ecosystem of microbes, but little is known about how the abundant bacteria in our gut interact with each other. In a new study published in Nature this week, Brigham and ...

Neuroscience

Loss of MHCI in motor neurons leads to ALS astrocyte toxicity

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating progressive neurodegenerative disease that results in the death of motor neurons, the nerve cells that control muscles. Eventually, ...

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