Immunology

Mitochondrial respiratory chain sustains inflammation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain—a series of protein complexes essential for a cellular respiration and energy production—is necessary for the activation ...

Oncology & Cancer

New review identifies four hallmarks of cancer metastasis

Researchers at the University of Alabama at Birmingham and the University of Kansas Cancer Center have identified four hallmarks of cancer metastasis—when cancer has spread to different parts of the body from where it started. ...

Diseases, Conditions, Syndromes

Physical frailty syndrome: A cacophony of multisystem dysfunction

In the inaugural issue of the journal Nature Aging a research team led by aging expert Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health, synthesizes converging evidence that the aging-related ...

Oncology & Cancer

Investigators uncover cellular pathway involved in cancer growth

The Cedars-Sinai investigators discovered several key components in the control of telomerase reverse transcriptase, or TERT, expression, one of the necessary component proteins of telomerase. High levels of TERT are found ...

Immunology

A pluralistic approach to thinking about the human microbiome

In "The Conceptual Ecology of the Human Microbiome," published in the June 2019 issue of The Quarterly Review of Biology, Nicolae Morar and Brendan J. M. Bohannan examine in detail the different metaphors scientists use to ...

Health

Cellular 'powerhouses' may explain health effects of stress

How does psychological stress translate into physical health effects? A key piece of the puzzle may be found in specialized cellular structures known as mitochondria, according to a pair of articles in the January issue of ...

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