Genetics
How pathogenic gene variants lead to heart failure
Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports in Science.
Aug 04, 2022
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News tagged with connective tissue cells
Neuroscience
Choroid plexus volume linked to Alzheimer's disease
Increased volume of an important structure in the brain called the choroid plexus is linked to greater cognitive impairment and Alzheimer's disease, according to a new study published in the journal Radiology.
May 17, 2022
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Oncology & Cancer
Patient-derived micro-organospheres enable cutting-edge precision oncology
A patient's tumor cell response to therapy is affected by many factors, including genetic alterations, tumor microenvironment, and intratumoral heterogeneity. This can make it extremely difficult to determine optimum treatment ...
May 05, 2022
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Neuroscience
Atherosclerotic plaques 'talk' with the brain
A new study shows the existence of a connection between atherosclerotic plaques and the central nervous system. This previously unknown "circuit" involves three systemically acting tissues, the immune system, the nervous ...
Apr 27, 2022
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249
Medical research
Liver fibrosis: The fatal signaling pathway
At least 5 million people in Germany suffer from liver disease. Fibrosis, the pathological proliferation of connective tissue, plays an important role in many complications of chronic liver problems. Activated hepatic stellate ...
Apr 27, 2022
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Oncology & Cancer
Distinct classes of fibroblasts in tumors play opposing roles, promoting or restraining pancreatic cancer growth
Researchers at The University of Texas MD Anderson Cancer Center have discovered that two distinct classes of cancer-associated fibroblasts (CAFs) accumulate in the pancreatic tumor microenvironment and play opposing roles ...
Mar 29, 2022
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Biomedical technology
Researchers successfully generate organoids in suspension, offering a new opportunity for investigators
During the past ten years, scientists who study how the human body develops and functions on the most basic level have enjoyed a renaissance of sorts, thanks to structures called organoids—tiny 3D models of organs developed ...
Feb 16, 2022
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Diseases, Conditions, Syndromes
Pimple secret popped: How fat cells in the skin help fight acne
Acne is among the most common skin diseases in the United States, according to the American Academy of Dermatology Association, affecting up to 50 million Americans each year. It is also among the least studied.
Feb 16, 2022
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Medical research
Origin of rare disease FOP rooted in muscle regeneration dysfunction
Fibrodysplasia ossificans progressiva (FOP) is a rare disease characterized by extensive bone growth outside of the normal skeleton that pre-empts the body's normal responses to even minor injuries. It results in what some ...
Jan 14, 2022
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Cardiology
Restoring heart elasticity in a heart failure model
Patients with heart failure often have shortness of breath and become fatigued quickly. They frequently suffer from water retention, heart palpitations, and dizziness. The condition can be triggered by a combination of elevated ...
Dec 01, 2021
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