Diseases, Conditions, Syndromes

Mechanism of fibrosis development discovered

Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease of unknown origin with limited treatment options. Research suggests that the signaling molecule WNT5A plays a key role in the pathogenic process. Now, a group ...

Cardiology

Heartbeat out of sync

Life-threatening cardiac arrhythmias often occur after a heart attack, as the scar tissue can interfere with the spread of electrical impulses that activate the heart. An international research team under the leadership of ...

Oncology & Cancer

New treatment for aggressive breast cancer

Approximately 10 to 15 percent of breast cancer cases do not respond to treatment with hormone therapy, which means that they are more aggressive and often recur. An international research team led by researchers at Lund ...

Cardiology

Researchers study a nanoscaffold for heart cells

Biophysicists from MIPT have studied the structure of a nanofibrous scaffold, as well as its interaction with rat cardiac cells. The study, which is part of the research into heart tissue regeneration, revealed that cardiomyocytes, ...

Diseases, Conditions, Syndromes

Pulmonary fibrosis caused by single transcription factor

To date, the molecular basis of pulmonary fibrosis has been poorly understood. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now shown that reduced activity of the transcription ...

Cardiology

MicroRNA molecule can cause pathological changes in the heart

Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. A team of researchers at the Technical University of Munich (TUM) has now discovered that microRNA 29 (miR-29) ...

Medical research

Turning brain cells into skin cells

A new study published in Nature Communications reveals that it is possible to repurpose the function of different mature cells across the body—and harvest new tissue and organs from these cells.

Oncology & Cancer

When healthy cells stimulate the migration of tumor cells

Estrogens act as a driving force of both healthy and cancerous mammary cell growth by binding to receptors that include a type named GPER, which is generally located in cell membranes. Recent studies have, however, revealed ...

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