Researchers at the UNC School of Medicine believe they have isolated a protein that, when missing or depleted, can cause airway constriction, production of mucus, chest tightness, and difficulty breathing for the 334 million ...
Feb 6, 2017
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A 39-year-old man with cystic fibrosis (CF) made history by becoming the first person in the world to receive human adult stem cells in a new research study that researchers hope will someday lead to the development of a ...
Jan 31, 2017
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The wear and tear of life takes a cumulative toll on our bodies. Our organs gradually stiffen through fibrosis, which is a process that deposits tough collagen in our body tissue. Fibrosis happens little by little, each time ...
Jan 30, 2017
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We think of the human immune system—for good reason—as our indispensable ally, our first line of defense against all kinds of invaders, including ones that can kill us if left unchecked. Yet in certain circumstances, ...
Oct 19, 2016
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According to the Cystic Fibrosis Foundation Patient Registry, more than 70,000 people worldwide are suffering from the disease, with approximately 1,000 new cases diagnosed each year in the United States alone. Adherence ...
Oct 18, 2016
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Horizon Pharma will spend about $800 million to buy Raptor Pharmaceutical and expand its portfolio of rare disease treatments, a growing area of focus for drugmakers.
Sep 12, 2016
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Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage. Several recent studies have suggested that a specific ...
Jul 21, 2016
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The lungs contain a thin layer of fluid known as the airway surface liquid (ASL), which helps protect against pathogens. The appropriate ASL volume, pH, and ionic composition are required for optimal airway defense. Cystic ...
Jun 2, 2016
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In experiments with isolated cystic fibrosis lung cells, University of Alabama at Birmingham researchers and colleagues from two other institutions have partially restored the lost function of those cells.
May 25, 2016
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The bacterium Burkholderia multivorans evolves and adapts in bursts to survive in the lungs of cystic fibrosis patients, according to a study published this week in mSystems, an open access journal from the American Society ...
May 24, 2016
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