One of the defining features of Covid-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.
Apr 16, 2020
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Cytokines, small proteins released by immune cells to communicate with each other, have for some time been investigated as a potential cancer treatment.
Jun 26, 2019
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Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed a key factor ...
Nov 19, 2012
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A new study by rheumatologists at Hospital for Special Surgery in New York has shown that a powerful pro-inflammatory protein, tumor necrosis factor (TNF), can also suppress aspects of inflammation. The researchers say the ...
May 22, 2011
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Chimeric antigen receptor T cells—CAR T cells for short—are immune cells (T cells) that are taken from the body and genetically modified outside the body in the laboratory using transport vehicles for the genes to be ...
Mar 22, 2024
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The inflammatory response is indispensable for protective immunity, yet microbial pathogens often trigger an excessive response, a "cytokine storm," harmful to the host. Despite recent advances in our understanding of inflammatory ...
Jul 19, 2023
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Following reports in June that the cheap steroid drug dexamethasone could help treat patients severely ill with COVID-19, scientists and clinicians urged caution. They were careful to highlight the need for further study ...
Sep 8, 2020
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Research into how the SARS-CoV-2 virus induces death is suggesting potential treatments for its most destructive complications.
May 20, 2020
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An international team of researchers led by prof. Savvas Savvides (VIB-UGent Center for Inflammation Research) has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, ...
Jan 17, 2018
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A high-risk subtype of acute lymphoblastic leukemia (ALL) first identified in children is highly prevalent in adults with ALL and is associated with a poor outcome, according to an international collaboration led by St. Jude ...
Nov 21, 2016
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