Diseases, Conditions, Syndromes

Researchers develop molecular traps to target SARS-CoV-2

A research team led by scientists at UC Riverside and UCLA has engineered novel nanoparticles to serve as "molecular traps" to target SARS-CoV-2, the virus that spreads COVID-19. The traps bind to SARS-CoV-2 and prevent it ...

Immunology

Roundworm quells obesity and related metabolic disorders

Researchers at the University of Maryland School of Medicine, Baltimore, have shown in a mouse model that infection with nematodes (also known as roundworms) can not only combat obesity but ameliorate related metabolic disorders. ...

Oncology & Cancer

Pre-op breast pain in about 28 percent of breast cancer patients

(HealthDay) -- More than a quarter of women about to undergo breast cancer surgery experience breast pain, with genetic polymorphisms in inflammatory cytokines correlating with pain, according to a study published in the ...

Diseases, Conditions, Syndromes

What role do cytokines play in autoimmune diseases?

Cytokines, a varied group of signaling chemicals in the body, have been described as the software that runs the immune system, but when that software malfunctions, dysregulation of the immune system can result in debilitating ...

Overweight & Obesity

Review: inflammation's role in obesity-colorectal cancer link

(HealthDay)—A new review summarizes the ways in which inflammation and altered metabolism are associated with colorectal cancer in obese individuals; the review was published online Sept. 3 in Obesity Reviews.

Neuroscience

Calcium channels regulate neuroinflammation and neuropathic pain

Northwestern Medicine investigators have discovered that specific calcium channels help regulate sex differences in the functioning of immune cells for neuroinflammation and overall neuropathic pain, according to findings ...

Medications

Oral deucravacitinib benefits patients with lupus

Tyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phase 2 clinical trial published in Arthritis & Rheumatology has ...

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