Certain T cells can secrete cytokines that are normally part of the innate immune system, as researchers from the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI) and an international research ...
Jan 5, 2023
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T cells aren't the first immune forces on the scene, they arrive after being alerted by other immune system warriors that a microbe has invaded or a cancer has silently seeded.
Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15)—a protein whose expression increases in response to cellular ...
Dec 16, 2022
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An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma. According to the new research from scientists at La Jolla Institute for Immunology (LJI), therapeutics ...
Dec 9, 2022
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Researchers at Karolinska Institutet in Sweden have shown that patients with acute COVID-19 infection have increased levels of the cytokine IL-26 in their blood. Moreover, high IL-26 levels correlate with an exaggerated inflammatory ...
Nov 17, 2022
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A new study, published recently in the journal Antibody Therapeutics, describes the discovery of a novel antibody which may have therapeutic potential by blocking the progression of inflammation caused by the cytokine interleukin-25 ...
Nov 16, 2022
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Astrocytes or astroglia, the largest glial cell population in the central nervous system (CNS), perform numerous vital functions. Among other things, these glial cells (i.e., cells supporting functions of the nervous system) ...
Tyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phase 2 clinical trial published in Arthritis & Rheumatology has ...
Nov 12, 2022
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Patients with cancer and a weakened immune system who are treated with immunotherapies tend to fare far worse from COVID-19 than those who haven't received such therapies in the three months before their COVID diagnosis, ...
Nov 3, 2022
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An article published in Science Advances suggests that a type of cancer treatment known as immune checkpoint blockade may be beneficial in certain cases of severe COVID-19. The creators of this therapy, which can successfully ...
Oct 27, 2022
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