The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19. When large numbers of immune cells release cytokines, this increases inflammation and creates a feedback ...
Aug 19, 2020
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In the early days of the COVID-19 pandemic, the SARS-CoV-2 virus seemed only rarely to have serious complications in children. However, by April 2020, pediatricians had begun recognizing a syndrome in children who tested ...
Jul 31, 2020
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Pro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopolysaccharide (LPS) are known to activate NF-kB. NF-kB is a master regulator of inflammation and induces pro-inflammatory cytokines. Although ...
Jul 16, 2020
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Chimeric antigen receptor T-cell therapy (CAR T) has proved to be a valuable treatment option for patients with lymphoma who have failed other therapies. In clinical trials, the cellular immunotherapy was shown to provide ...
Jul 15, 2020
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It's a trajectory followed by many who experience a severe case of COVID-19: They feel poorly for a few days, improve over a day or two and then, a week or 10 days into their infection, have respiratory difficulties, a stroke, ...
Jul 8, 2020
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Doctors can examine COVID-19 patients' blood to identify those at greatest risk of severe illness and to pinpoint those most likely to need a ventilator, new research from the University of Virginia School of Medicine suggests.
Jun 30, 2020
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The name 'cytokine storm' is apt: It describes a furious gale-force swarm of molecules unleashed by the body's immune system that causes extreme inflammation, tissue damage, even death. Cytokines—from the Greek cyto for ...
Jun 29, 2020
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Scientists at the Stowers Institute for Medical Research have shown that a dysfunctional placenta can play a previously unrecognized role during the earliest stages of development in mouse models of Cornelia de Lange syndrome. ...
Jun 16, 2020
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Scientists at St. Jude Children's Research Hospital, UCSF Benioff Children's Hospitals and Baylor College of Medicine are investigating how to best treat hemophagocytic lymphohistiocytosis (HLH), a rare immune disorder. Their ...
Jun 12, 2020
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Known as the French paradox, a low incidence of coronary heart disease despite substantial intake of saturated fats is thought to be due to a diet rich in polyphenols. Polyphenols are abundant in plant based foods such as ...
Jun 10, 2020
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