For patients with pretreated relapsed and refractory multiple myeloma, idecabtagene vicleucel (ide-cel), a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy, prolongs progression-free survival and ...
Feb 10, 2023
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Northwestern Medicine investigators have discovered that specific calcium channels help regulate sex differences in the functioning of immune cells for neuroinflammation and overall neuropathic pain, according to findings ...
Jan 30, 2023
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Higher levels of daily physical activity are associated with reduced susceptibility to upper respiratory tract infections such as the common cold, suggests a study of 104 Polish children published in Pediatric Research.
Jan 23, 2023
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Interleukin (IL)-15 is a cytokine with different modes of action, and a new article describes why it is important to selectively target the mode of action of the cytokine rather than IL-15 itself to inhibit its activity. ...
Jan 23, 2023
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Certain T cells can secrete cytokines that are normally part of the innate immune system, as researchers from the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI) and an international research ...
Jan 5, 2023
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T cells aren't the first immune forces on the scene, they arrive after being alerted by other immune system warriors that a microbe has invaded or a cancer has silently seeded.
Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15)—a protein whose expression increases in response to cellular ...
Dec 16, 2022
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An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma. According to the new research from scientists at La Jolla Institute for Immunology (LJI), therapeutics ...
Dec 9, 2022
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Researchers at Karolinska Institutet in Sweden have shown that patients with acute COVID-19 infection have increased levels of the cytokine IL-26 in their blood. Moreover, high IL-26 levels correlate with an exaggerated inflammatory ...
Nov 17, 2022
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A new study, published recently in the journal Antibody Therapeutics, describes the discovery of a novel antibody which may have therapeutic potential by blocking the progression of inflammation caused by the cytokine interleukin-25 ...
Nov 16, 2022
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