The term anhedonia is used to describe the inability to feel pleasure and a disinterest in activities that previously brought positive feelings. This lack of interest and pleasure is a very common symptom of depression, as ...
Scientists at the Centre for Addiction and Mental Health (CAMH) have identified a novel drug target that could lead to the development of better antipsychotic medications.
Dec 9, 2014
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Brain scans of two strains of mice imbibing significant quantities of alcohol reveal serious shrinkage in some brain regions - but only in mice lacking a particular type of receptor for dopamine, the brain's "reward" chemical. ...
Feb 15, 2012
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(Medical Xpress) -- Researchers have long known that dopamine, a brain chemical that plays important roles in the control of normal movement, and in pleasure, reward and motivation, also plays a central role in substance ...
Jul 12, 2011
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Visitors to the Oktoberfest have always known it and now it has been scientifically proven – beer can lift your spirits. Scientists at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) examined 13,000 food components ...
Sep 29, 2017
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People who are alcohol-dependent and who also carry a particular variant of a gene run an increased risk of premature death. This is a recent finding from the interdisciplinary research at the Department of Psychology and ...
Nov 15, 2011
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The cerebellum is essential for sensorimotor control but also contributes to higher cognitive functions including social behaviors. In a recent study, an international research consortium including scientists from Inserm—University ...
Jun 16, 2022
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The dopamine D2 receptor has a previously unobserved role in modulating Wnt expression and control of cell proliferation, according to a new study from the George Washington University (GW) and the University of Pittsburgh. ...
Nov 14, 2019
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Dopamine deficiency in the basal ganglia (a set of subcortical structures) causes severe motor dysfunctions, such as slowness of movements (bradykinesia), as observed in Parkinson's disease. Dopamine binds D1 and D2 receptors ...
Oct 6, 2015
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Since their development in the 1950s, antipsychotic drugs have been widely used to treat psychoses and neuropsychiatric disorders like schizophrenia. A debilitating side-effect of these drugs called parkinsonism limits their ...
Jul 6, 2016
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