Immunology

Why protecting the brain against infection takes guts

The brain is uniquely protected against invading bacteria and viruses, but its defence mechanism has long remained a mystery. Now, a study in mice, confirmed in human samples, has shown that the brain has a surprising ally ...

Oncology & Cancer

A heart-breast-cancer-on-a-chip monitoring system

Breast cancer is the most commonly occurring cancer for women around the world, and much effort has been spent in the development of therapies to treat this disease. Among these treatments, chemotherapy has been shown to ...

Genetics

DNA webs may drive lung pathology in severe COVID-19

Sticky webs of DNA released from immune cells known as neutrophils may cause much of the tissue damage associated with severe COVID-19 infections, according to two new studies published September 14 in the Journal of Experimental ...

Oncology & Cancer

Protein causes mutations that lead to breast cancer cell aggression

Like most scientists, University of Alberta biochemist Ing Swie Goping is curious. When her team discovered that a protein was associated with poor outcomes in breast cancer patients, she wanted to know why. Now, that curiosity ...

Neuroscience

Microglia might lessen seizure severity in epilepsy

New research in mice highlights the potential protective effect of microglia—a type of non-neuronal cell in the brain—against overactivation of the central nervous system during acute epileptic seizures. The study is ...

Neuroscience

Probe detects the destruction of defective mitochondria

A versatile probe that can detect with pinpoint accuracy the programmed destruction of defective mitochondria—the powerhouses of cells—has been developed by RIKEN researchers. They used it to show that damaged mitochondria ...

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