Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a progressive, fatal neurological disease that attacks the nerve cells controlling voluntary muscles. No effective treatments have been found.
Nov 7, 2016
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Many chemotherapy drugs work by damaging cancer cells' DNA so severely that the cells are forced to commit cellular suicide. However, these drugs don't work for all patients: If cells can repair the DNA damage, they may survive ...
Nov 2, 2016
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Progressively shortening telomeres—the protective caps on the end of chromosomes—may be responsible for the weakened, enlarged hearts that kill many sufferers of Duchenne muscular dystrophy, according to a study by researchers ...
Oct 31, 2016
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Researchers have discovered a novel mechanism in a combination drug therapy that shows potential as a new approach for treating acute myeloid leukemia (AML) and many other cancers. When combined, these agents cause interactions ...
Oct 10, 2016
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The capacity of formaldehyde, a chemical frequently used in manufactured goods such as automotive parts and wood products, to damage DNA, interfere with cell replication and cause cancer inspired new federal regulations this ...
Sep 29, 2016
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Stanford researchers have found that a tumor suppressor known as p53 is stabilized by a regulatory RNA molecule called DINO. The interaction helps a cell respond to DNA damage and may play a role in cancer development and ...
Sep 26, 2016
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Scientists from Harvard Medical School have identified a key instigator of nerve cell damage in people with amyotrophic lateral sclerosis, or ALS, a progressive and incurable neurodegenerative disorder.
Aug 24, 2016
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Heart muscle cells made from induced pluripotent stem cells faithfully mirror the expression patterns of key genes in the donor's native heart tissue, according to researchers at the Stanford University School of Medicine. ...
Aug 18, 2016
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What happens when red blood cells become damaged or reach the end of their normal life span, and how is the iron required for carrying oxygen recycled? A new study led by Massachusetts General Hospital (MGH) investigators ...
Jul 18, 2016
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Researchers at the University of Copenhagen have discovered a molecular mechanism that reads so-called epigenetic information and boosts repair of lesions in our DNA. This knowledge can be used to develop new targeted cancer ...
Jun 22, 2016
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