Medical research
Reducing double-strand DNA break repair exacerbates vascular aging, study finds
A new research paper was published in Aging, titled "Reduction of double-strand DNA break repair exacerbates vascular aging."
Oct 18, 2023
0
0
Page 3 - News tagged with damage dna
Cardiology
Investigating the role of DNA damage in cardiac hypertrophy
A novel cellular pathway regulates DNA damage and structural changes in cardiomyocytes, which contributes to the development of cardiac hypertrophy, according to a Northwestern Medicine study published in Circulation.
Oct 12, 2023
0
1
Genetics
Decoding the complexity of Alzheimer's disease
Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.
Sep 28, 2023
0
22
Parkinson's & Movement disorders
New blood test detects a key indicator of Parkinson's disease
Researchers have developed a blood test that detects Parkinson's disease, potentially establishing a way to help diagnose the condition before nervous system damage worsens.
Aug 30, 2023
0
80
Addiction
Understanding mechanisms of alcohol-associated bowel disease
Alcohol consumption is a significant risk factor for gastrointestinal diseases, including cancer. Alcohol can damage the gastrointestinal tract in several ways. It can promote an impairment of several intestinal barrier functions, ...
Aug 21, 2023
0
2
Genetics
Scientists link obesity to sex- and age-specific genes
From influencing how our body stores fat to how our brain regulates appetite, hundreds of genes, along with environmental factors, collectively determine our weight and body size.
Aug 2, 2023
0
19
Medications
Researchers find timing, dosage of DNA-damaging drugs are key to whether a cancer cell dies or enters senescence
Despite the proliferation of novel therapies such as immunotherapy or targeted therapies, radiation and chemotherapy remain the frontline treatment for cancer patients. About half of all patients still receive radiation and ...
Jul 28, 2023
0
11
Oncology & Cancer
LP-284 targets non-Hodgkin's lymphoma and DNA damage repair deficiency
A new research paper titled "LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair" has been published in Oncotarget.
Jun 12, 2023
0
27
Medical research
DNA replication discovery opens paths to understanding and treating cancer, aging and degenerative disease
An international collaboration steered by David Cortez, Richard N. Armstrong, Ph.D. Chair for Innovation in Biochemistry, explored how cells tolerate DNA damage and genome instability—and they arrived at conclusions that ...
May 3, 2023
0
42
Oncology & Cancer
Researchers identify promising new target for drug-resistant breast and ovarian cancers
CU Boulder researchers have discovered a protein's crucial role in helping breast and ovarian tumors survive and thrive and have found that suppressing that protein kills cancer cells without harming healthy ones.
Apr 13, 2023
0
47
