Diseases, Conditions, Syndromes

Cellular antiviral defenses

Nonsense-mediated mRNA decay (NMD) is a quality control mechanism that regulates levels of both aberrant and wild-type cellular RNAs. It also contributes to antiviral immunity against select plant and human RNA viruses. However, ...

Dentistry

Complexity of human tooth enamel revealed at atomic level

Scientists used a combination of advanced microscopy and chemical detection techniques to uncover the structural makeup of human tooth enamel at unprecedented atomic resolution, revealing lattice patterns and unexpected irregularities. ...

Dentistry

Study reveals how too much fluoride causes defects in tooth enamel

Exposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel—a novel explanation for how dental fluorosis, a condition caused by overexposure ...

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