Europe's medicines watchdog on Friday rejected a marketing request for a new Alzheimer's disease treatment, saying the risks of the medicine's side effects, including potential brain bleeding, outweighed the benefits.
16 hours ago
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Northwestern Medicine scientists have discovered that mitochondria are not necessary for the proliferation of specialized immune cells in the central nervous system, but do help those cells respond to demyelinating injuries, ...
17 hours ago
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Alzheimer's disease (AD) is marked by severe neurodegeneration and cognitive decline, presenting significant challenges for its prevention and treatment. Traditional hypotheses have focused on amyloid-beta plaques and Tau ...
Jul 25, 2024
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New research led by UCLA Health has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing insights useful to doctors developing targeted therapies.
Jul 24, 2024
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Walking requires a huge number of signals between your brain and the muscles in your arms, chest, back, abdomen, pelvis and legs. Something that looks relatively straightforward is in fact incredibly complex. And the pace ...
Jul 24, 2024
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An MIT study published in Nature provides new evidence for how specific cells and circuits become vulnerable in Alzheimer's disease, and hones in on other factors that may help some people show resilience to cognitive decline, ...
Jul 24, 2024
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Data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study, the first and largest clinical trial of pre-symptomatic Alzheimer's disease, is now widely available to researchers studying the condition. The ...
Jul 23, 2024
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Research has shown that about 40% of dementia could be prevented or delayed worldwide by addressing modifiable risk factors associated with the condition, particularly during midlife.
Jul 17, 2024
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A new study of middle-aged and older adults looks at sex differences in frailty levels and their link with heart health. The findings suggest that moving your body more through regular exercise and sitting less can help keep ...
Jul 17, 2024
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A significant discovery by Australian scientists has the potential to improve the effectiveness of drugs currently used to manage cognitive decline in patients with Alzheimer's disease.
Jul 17, 2024
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Decline is a change over time from previously efficient to inefficient organizational functioning, from previously rational to non-rational organizational and individual decision-making, from previously law-abiding to law violating organizational and individual behavior, from previously virtuous to iniquitous individual moral behavior. Note: The word decline should not be confused with the word obsolete. Decline refers to the degenerating of something whereas obsolete refers to the outdating of something or that it is no longer in use. It is the process of declining, a gradual sinking and wasting away.
Social decline or moral decline is typically characterised as reduced adherence to cultural or social norms or values and widespread lapses in ethical behavior.
Entities and organizations may enter a state of decline if they fail to respond effectively to changes, because they :
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