Medical research

Cell-cell signals in developing heart

During late stages of heart development, interactions between the endocardium (the inner layer of cells) and the myocardium (the heart muscle) are known to be crucial. Signaling between these two cell layers during the earliest ...

Pediatrics

First-ever in-utero surgery to treat spina bifida

A team of specialists at UPMC Magee-Womens Hospital and UPMC Children's Hospital of Pittsburgh have performed UPMC's first in-utero surgery to close an open neural tube defect in a baby months before her birth.

Medications

FDA approves $2M medicine, most expensive ever

U.S. regulators have approved the most expensive medicine ever, for a rare disorder that destroys a baby's muscle control and kills nearly all of those with the most common type of the disease within a couple of years.

Cardiology

Surgeon who transplanted baboon heart into baby dies

Dr. Leonard Bailey, who in 1984 transplanted a baboon heart into a tiny newborn dubbed "Baby Fae" in a pioneering operation that sparked both worldwide acclaim and condemnation, has died. He was 76.

Diseases, Conditions, Syndromes

Rheumatoid arthritis drug diminishes Zika birth defects in mice

In experiments with pregnant mice infected with the Zika virus, Johns Hopkins Medicine researchers report they have successfully used a long-standing immunosuppressive drug to diminish the rate of fetal deaths and birth defects ...

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