Immunology

Immune cells drive gallstone formation

Sticky meshworks of DNA and proteins extruded by white blood cells called neutrophils act as the glue that binds together calcium and cholesterol crystals during gallstone formation, researchers in Germany report August 15 ...

Genetics

A new framework to study congenital heart defects

Each year, 9 months of dreams and anticipation shared by millions of parents-to-be turn to despair and fright when learning their child is born with a birth defect; an often-devastating event affecting one out of 20 children ...

Medical research

Cell-cell signals in developing heart

During late stages of heart development, interactions between the endocardium (the inner layer of cells) and the myocardium (the heart muscle) are known to be crucial. Signaling between these two cell layers during the earliest ...

Medications

FDA approves $2M medicine, most expensive ever

U.S. regulators have approved the most expensive medicine ever, for a rare disorder that destroys a baby's muscle control and kills nearly all of those with the most common type of the disease within a couple of years.

Oncology & Cancer

Researchers identify one way T cell function may fail in cancer

The immune system is an important defender against cancer. Immune cells continuously search the body for disease and use their anti-tumor cell properties to target and destroy defective cells. However, most cancer patients ...

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