The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a new study publishing July 5 in the open-access journal PLOS Biology by Daesung ...
Jul 5, 2022
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Doxorubicin, a 50-year-old chemotherapy drug still in widespread use against a variety of cancers, has long been known to destroy heart tissue, as well as tumors, in some patients.
Oct 28, 2012
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Stem cells drawn from amniotic fluid show promise for tissue engineering, but it's important to know what they can and cannot do. A new study by researchers at Rice University and Texas Children's Hospital has shown that ...
May 2, 2013
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University of Michigan researchers have determined how a gene that is known to be defective in Down syndrome is regulated and how its dysregulation may lead to neurological defects, providing insights into potential therapeutic ...
Jun 5, 2013
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A preclinical study by a University of South Florida Health (USF Health) Morsani College of Medicine research team has discovered a new mechanism for how Zika virus can pass from mothers to their children during pregnancy—a ...
Feb 3, 2021
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Fatih Uckun, Jianjun Cheng and their colleagues have taken the first steps towards developing a so-called "smart bomb" to attack the most common and deadly form of childhood cancer—called B-lineage acute lymphoblastic leukemia ...
Nov 5, 2014
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News of the discovery of herbal cancer treatments has always piqued people's interest. Recently, the media in Indonesia extensively reported claims of a cancer cure made from a plant native to Borneo and the use of soursop ...
Sep 4, 2019
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Cardiovascular diseases (CVD) lead to atherosclerosis and heart failure and are prevalent age-related illnesses in humans. In a new study, published in the renowned journal JCI, scientists from Roland Foisner's group at the ...
Jan 8, 2019
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Stanford Medicine investigators and their colleagues sifted through a jumble of genes implicated in neurodevelopmental disorders and identified dozens of disparate troublemakers with similar effects.
Sep 27, 2023
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The ATR protein plays an important role in the response to replication stress as a regulator of the DNA damage response (DDR) and controls cell viability. Mutations of ATR in humans lead to, among other pathologies, neurological ...
Jul 6, 2021
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