Health

Child deaths in Africa could be prevented by family planning

Children under 5 years of age in Africa are much more likely to die than those in wealthy countries as a direct result of poor health outcomes linked to air pollution, unsafe water, lack of sanitation, an increased family ...

Medical research

Novel paradigm in drug development

Traditional medicines mostly function as inhibitors, attacking the disease-relevant proteins that cause cancer, by binding to their accessible pockets. Following this strategy, only ~20% of all proteins are chemically addressable, ...

Medical research

New pharmaceutical target reverses osteoporosis in mice

Biomedical engineers at Duke University have discovered a pharmaceutical target that, when activated, can reverse bone degradation caused by osteoporosis in mouse models of the disease.

Medical research

Defective degradation enzyme triggers hereditary storage diseases

In rare hereditary storage diseases such as Sandhoff's disease or Tay-Sachs syndrome, the metabolic waste from accumulating gangliosides cannot be properly disposed of in the nerve cells because important enzymes are missing. ...

Alzheimer's disease & dementia

New mechanism detected in Alzheimer's disease

McGill University researchers have discovered a cellular mechanism that may contribute to the breakdown of communication between neurons in Alzheimer's disease.

Alzheimer's disease & dementia

New strategy may help combat Alzheimer's disease

Researchers have uncovered a mechanism that helps block the accumulation of proteins involved in Alzheimer's disease. Tapping into this natural process may therefore help prevent or treat the condition.

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Degradation

Degradation may refer to;

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