Immune checkpoint inhibitors that activate T cells to target cancer cells have greatly improved patient outcomes across a variety of tumor types. But not all patients respond to the therapies. Moffitt Cancer Center researchers ...
Feb 13, 2023
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Anti-cancer immune cells are critical to inhibiting the development and progression of tumors, and deregulation of the immune system can limit the ability of immune cells to identify and target cancer cells for destruction. ...
Oct 10, 2022
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Cells from the immune system called CD4+ regulatory T cells, or simply Treg, are linked to tumor prognosis: the more Treg cells present in a tumor, the worst the prognosis. We know from previous research studies that Treg ...
Nov 29, 2021
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In the human body, so-called dendritic cells are responsible for activating our immune system. While researchers previously believed that tumors could repress these dendritic cells – blocking an adequate natural cancer ...
Jan 25, 2017
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