Oncology & Cancer

How immune cells in the tumor microenvironment make things worse

Cells from the immune system called CD4+ regulatory T cells, or simply Treg, are linked to tumor prognosis: the more Treg cells present in a tumor, the worst the prognosis. We know from previous research studies that Treg ...

Immunology

Bone marrow backup needed to tackle respiratory infections

Scientists at the Francis Crick Institute have found how the immune system triggers an 'emergency' dendritic cell response during infection, with dendritic cells at the site of infection being reinforced by new cells which ...

Diseases, Conditions, Syndromes

How COVID-19 alters the immune system

COVID-19 reduces the numbers and functional competence of certain types of immune cells in the blood, say LMU researchers. This could affect responses to secondary infections.

Arthritis & Rheumatism

A two-pronged approach to keep rheumatoid arthritis in check

Rheumatoid arthritis (RA) is an autoimmune, inflammatory disease. Though the precise mechanism of the disease is only partially understood, people with RA produce antibodies that target their own tissues, contributing to ...

Diseases, Conditions, Syndromes

A promising two-punch therapy for Langerhans cell histiocytosis

Langerhans cell histiocytosis (LCH) is a rare cancer involving dendritic cells, a type of white blood cell that usually helps defend against infections. The current standard of care for LCH, chemotherapy, cures fewer than ...

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