Diseases, Conditions, Syndromes

People's initial immune response to dengue fever analyzed

Researchers have come one step closer to understanding how the immune system responds to acute dengue fever, a disease that has affected hundreds of thousands of people in Southeast Asia this summer alone. In a study published ...

Medical research

Possible treatment on the horizon for severe dengue disease

Researchers led by Duke-NUS Medical School have discovered that tryptase, an enzyme in human cells that acts like scissors to cut up nearby proteins, is responsible for blood vessel leakage in severe dengue hemorrhagic fever. ...

Diseases, Conditions, Syndromes

Scientists uncover mechanism behind development of viral infections

A team of researchers from the SingHealth Duke-NUS Academic Medicine Centre's Viral Research and Experimental Medicine Centre (ViREMiCS) found that immune cells undergoing stress and an altered metabolism are the reasons ...

Diseases, Conditions, Syndromes

A new picture of dengue's growing threat

Research published today in Nature Microbiology paints a startling new picture of where dengue, the world's fastest-growing mosquito-borne virus, will spread to put more than 6 billion people at risk toward the end of the ...

Diseases, Conditions, Syndromes

Mother's dengue immunity worsens baby's response to Zika

Researchers at Duke-NUS Medical School and their colleagues have identified a surprising interaction between dengue and Zika viruses that sheds lights on the significant fetal brain abnormalities linked to Zika virus.

Diseases, Conditions, Syndromes

Study traces the origins of Chikungunya in Brazil

New evidence suggests that Chikungunya virus arrived in Brazil at least one year earlier than it was detected by public health surveillance systems. Scientists at the Center for Infection and Immunity (CII) at the Columbia ...

Diseases, Conditions, Syndromes

Prior dengue infection protects against Zika

The higher a person's immunity to dengue virus, the lower their risk of Zika infection, an international team of scientists led by the University of Pittsburgh Graduate School of Public Health, Yale School of Public Health ...

Genetics

Set of genes predicts severity of dengue, study reports

There's no such thing as a "good" case of dengue fever, but some are worse than others, and it's difficult to determine which patients will make a smooth recovery and which may find their condition life-threatening.

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