Diseases, Conditions, Syndromes

Can we withdraw treatment in post-menopausal osteoporosis?

Bisphosphonates are the recommended first-line treatment in post-menopausal osteoporosis, with denosumab recommended second-line. Based on the length of clinical trials for bisphosphonates, these drugs are usually prescribed ...

Medications

Therapy for rare bone disorder shows promise in clinical trial

A clinical trial at the National Institutes of Health found that a medication, denosumab, significantly reduced abnormal bone turnover in adults with fibrous dysplasia, a rare disease marked by weak and misshapen bones. Bone ...

Gerontology & Geriatrics

Osteoporosis drug prescribing often does not follow guidelines

Less than one in 10 commercially insured patients in the United States who broke a hip, a major complication of osteoporosis, receive any osteoporosis medical treatment within two calendar quarters of their fracture, according ...

Medications

Vertebral fractures up with long-term delay of denosumab

(HealthDay)—Compared with on-time dosing, delay of denosumab by more than 16 weeks is associated with an increased risk for vertebral fractures, according to a study published online July 28 in the Annals of Internal Medicine.

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