Neuroscience
A new role for neurogenesis
The ability to create new neurons may exist as built-in protection for sensitive brain areas, according to research in mice recently published in JNeurosci.
Jan 20, 2020
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News tagged with dentate gyrus
Medical research
New neurons take six months or more to mature in non-human primate brain
New neurons take more than six months to mature in adult monkeys and that time is likely even longer in humans, according to researchers at the University of Pittsburgh School of Medicine, the University of Illinois, and ...
Jun 6, 2011
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Neuroscience
Lateral inhibition keeps similar memories apart
When you park in the office car park, you usually have no problem finding your car again at the end of the day. The next day, you might park a few spots further away. However, in the evening, you find your car, even though ...
Nov 5, 2018
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Neuroscience
Scientists watch activity of newborn brain cells in mice; reveal they are required for memory
Columbia neuroscientists have described the activity of newly generated brain cells in awake mice—a process known as adult neurogenesis—and revealed the critical role these cells play in forming memories. The new research ...
Mar 10, 2016
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Neuroscience
Portion of hippocampus found to play role in modulating anxiety
Columbia University Medical Center (CUMC) researchers have found the first evidence that selective activation of the dentate gyrus, a portion of the hippocampus, can reduce anxiety without affecting learning. The findings ...
Mar 6, 2013
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Neuroscience
Gene that enables memories, sense of direction produces schizophrenia-like symptoms when mutated
Mutations in a gene that should enable memories and a sense of direction instead can result in imprecise communication between neurons that contributes to symptoms of schizophrenia, scientists report.
Jan 18, 2017
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Neuroscience
Alzheimer's risk gene impairs development of new neurons in mice
Scientists have taken a step closer to understanding how the strongest known genetic risk factor for Alzheimer's disease (AD) contributes to memory impairment. Reporting their findings in eNeuro, the researchers demonstrate ...
Jul 30, 2018
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Medical research
Medical center identifies role of neuron creation in anxiety disorders
(Medical Xpress)—People with anxiety disorders such as post-traumatic stress disorder (PTSD) often have impaired pattern separation—the process by which similar experiences are transformed into distinct memories. They ...
Jan 24, 2013
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Medical research
Lipid metabolism regulates the activity of adult neural stem cells
(Medical Xpress)—Neural stem cells in the adult brain boost their levels of lipid metabolism to grow and generate new neurons. This new finding may open novel therapeutic avenues to treat age- or disease-associated loss ...
Dec 4, 2012
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Diseases, Conditions, Syndromes
Cell antennas lacking in Fragile X syndrome, study finds
Structures called primary cilia—which act like TV antennas for cells to detect signals—are present in fewer numbers in mice born with Fragile X syndrome, according to researchers from The University of Texas Health Science ...
Jul 30, 2020
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