In recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have been highly successful and have become an important basis for the future treatment of cancers. However, the absence of tumoral ...
Sep 12, 2023
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Researchers at The University of Texas MD Anderson Cancer Center have uncovered a functional role for KRAS mutations in pancreatic cancer and rapidly translated these findings into a novel therapeutic approach combining a ...
Aug 24, 2023
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Scientists have relied on animal models as an alternative to testing on human tissues and cells for decades. But not just any organism can adequately model how human cells behave. Researchers take into account how quickly ...
Aug 8, 2023
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Researchers at Masaryk University, Czech Republic, have innovated a technique to track bone development, growth dynamics and healing in a mouse model. In their paper, "Spatiotemporal monitoring of hard tissue development ...
Spontaneous rhythmic contractions of the intestinal tract, also known as peristalsis, play an important role in enabling healthy gut function in the vast majority of living organisms. This intrinsic activity appears to be ...
Aug 3, 2023
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The lifespan of a small roundworm that has been used as a key model organism in aging research is limited by how it self-sacrifices to feed its young, finds a new study led by UCL researchers.
Jul 26, 2023
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A research team led by Northwestern University and the University of Pennsylvania scientists has created a new synthetic biology approach, a "QR code for cancer cells," to follow tumor cells over time, finding there are meaningful ...
Jul 19, 2023
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Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.
Jul 14, 2023
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While the importance of the triggering receptor expressed on myeloid cells 2 (TREM2) is known in brain microglial function during neurodegenerative diseases, the function of the TREM2 cell receptor/protein is unknown in glioblastoma ...
Sensory cells in the vagus nerve can detect and locate food in the esophagus. Their signals help transport the food onward to the stomach. Signal failure leads to swallowing disorders, say a team led by Carmen Birchmeier ...
May 26, 2023
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