Genetics
Team seeks to create genetic map of worm's nervous system
How do you build a brain? What "rules" govern where neurons end up, how they connect to each other, and which functions they perform?
Dec 10, 2018
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News tagged with developmental genes
Genetics
Study connects the genetic background of autistic spectrum disorders with stem cell dysfunction
Disorders of the autistic spectrum have been associated with hundreds of genetic variations, which have helped in identifying disturbed intracellular signalling pathways and molecular mechanisms typical to autism.
Dec 4, 2018
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13
Genetics
Recessive genes explain only small fraction of undiagnosed developmental disorders
The Deciphering Developmental Disorders study has discovered that only a small fraction of rare, undiagnosed developmental disorders in the British Isles are caused by recessive genes. The study by researchers from the Wellcome ...
Nov 8, 2018
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37
Genetics
Largest autism sequencing study to date yields 102 genes associated with ASD
In the largest genetic sequencing study of autism spectrum disorder (ASD) to date, researchers have identified 102 genes associated with ASD, and report significant progress toward teasing apart the genes associated with ...
Oct 17, 2018
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5
Genetics
Searching for a diagnosis: How scientists are untangling the mystery of developmental disorders
Evie Walker sits on Alison's lap, playing a game she never grows tired of: turning her mum's hand over and over, stroking and examining it. When she takes a break and looks around, it is with the open-mouthed look of curiosity ...
Sep 18, 2018
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1
Medical research
New model for predicting neuroblastoma outcomes incorporates early developmental signals
Neuroblastoma, a rare childhood cancer of the sympathetic nervous system, is particularly deadly because it is difficult to detect and thus generally advanced before treatment begins. Scientists know that neuroblastoma develops ...
Jul 6, 2018
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28
Genetics
Scientists identify new way cells turn off genes
Cells have more than one trick up their sleeve for controlling certain genes that regulate fetal growth and development.
Jul 19, 2017
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497
Genetics
CRKL in 22q11.2; a key gene that contributes to common birth defects
The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in about 1 in 4,000 births, causing the loss or duplication of up to 40 genes. ...
May 25, 2017
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12
Neuroscience
CD38 gene is identified to be important in postnatal development of the cerebral cortex
The brain consists of neurons and glial cells. The developmental abnormality of glial cells causes various diseases and aberrant cerebral cortex development. CD38 gene knockout is shown to cause aberrant development of glial ...
Apr 7, 2017
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2
Medical research
Reactivation of embryonic genes leads to muscle aging
Developmental genes and pathways strictly regulate embryogenesis. The process is strongly driven by so-called Hox-genes. Now, researchers from the Leibniz Institute on Aging (FLI) in Jena, Germany, can show that one of these ...
Dec 1, 2016
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