Oncology & Cancer

Identifying new targeted therapy approaches for leukemia

A team of Northwestern Medicine scientists led by Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, has identified the molecular mechanisms of ASXL1 mutations ...

Neuroscience

RNA scientists identify many genes involved in neuron development

Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells ...

Genetics

'Hidden biological link' among autism genes revealed in study

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis—a process in which specialized "progenitor" cells give rise to new brain cells—in the development ...

Medical research

Study reveals surprising variability of muscle cells

Usually, each cell has exactly one nucleus. But the cells of our skeletal muscles are different: These long, fibrous cells have a comparatively large cytoplasm that contains hundreds of nuclei. But up to now, we have known ...

Neuroscience

Scientists take major step toward Angelman Syndrome gene therapy

Babies born with a faulty maternal copy of the UBE3A gene will develop Angelman syndrome, a severe neurodevelopmental disorder with no cure and limited treatments. Now, for the first time, scientists at the UNC School of ...

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