Medical research

A tale of two proteins: The best and worst of metabolic adaptation

The Developmental Origins of Health and Disease (DOHaD) hypothesis is supported by multiple human epidemiological studies and animal studies. It states that the nutritional environment in early life makes people susceptible ...

Genetics

Genes could play a role in tooth decay and gum disease

Tooth decay and gum disease impact on illness and healthcare spending, yet the role of genetics in dental problems is largely unknown. New research led by an international team, including researchers at the University of ...

Cardiology

Cardiac genetic mutation may not always predict heart disease

More than 750,000 people in the United States have dilated cardiomyopathy, a potentially life-threatening condition in which the heart's main pumping chamber, the left ventricle, enlarges and grows increasingly weak. Research ...

Medications

New method divides patients with ulcerative colitis in groups

Researchers at Karolinska Institutet in Sweden have found a way of using gene expression conserved across species to divide patients with the inflammatory bowel disease ulcerative colitis into two distinct groups. The findings ...

Medical research

First in vivo proof-of-concept in Steinert's myotonic dystrophy

Ana Buj Bello's team, a researcher in an Inserm unit at Genethon, the AFM-Telethon laboratory, has made the proof-of-concept of a CRISPR-Cas9 approach in a mouse model of Steinert's myotonic dystrophy, the most common neuromuscular ...

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