A breakthrough genetic discovery from researchers at the Schulich School of Medicine & Dentistry at the University of Western Ontario is unlocking new clues about why some individuals experience early onset of neurodegenerative ...
Nov 29, 2021
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Ludwig Maximilians University Munich (LMU) immunologists have discovered how mutations in Roquin-1 trigger autoimmunity, but can also improve the body's fight against cancer cells.
Nov 26, 2021
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According to the commonly accepted model, Alzheimer's disease is characterized by an ineluctable sequence, from the accumulation of toxic proteins in the brain to dementia resulting from neurodegeneration. While this deterministic ...
Nov 23, 2021
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Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver unrelated to alcohol abuse or other liver diseases. It is often associated with obesity and diabetes and is considered a manifestation of metabolic ...
Nov 10, 2021
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Researchers identified almost two dozen genes that contribute to heart defects by studying genetic data from people born with congenital heart disease or autism. Hongyu Zhao of Yale University and colleagues developed a new ...
Nov 4, 2021
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Stem cell researchers may soon have a new way to identify and develop novel, personalized therapies for patients with Cystic Fibrosis (CF) who lack effective treatments.
Oct 21, 2021
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For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease. These mutations are specific to liver disease that is associated with obesity, ...
Oct 13, 2021
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The structural integrity of the brain's white matter as measured with an advanced MRI technique is lower in cognitively normal people who carry a genetic mutation associated with Alzheimer's disease than it is in non-carriers, ...
Oct 12, 2021
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Huntington's disease is a fatal condition involving the death of brain cells, typically striking in midlife. But new findings suggest the disease process starts decades earlier. Although symptoms emerge in adulthood, researchers ...
Oct 5, 2021
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A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory ...
Sep 2, 2021
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