Myelodysplastic syndrome is an umbrella term used to describe disorders characterized by the bone marrow's inability to produce normal blood cells. Researchers from Charité - Universitätsmedizin Berlin have found that a ...
Apr 12, 2017
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Investigators at the Massachusetts General Hospital (MGH) Cancer Center have identified the first genetic mechanisms conferring acquired resistance to a promising group of targeted cancer drugs. In a paper appearing in the ...
Mar 23, 2017
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African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants - named G1 and G2—in APOL1, a gene that codes for a human-specific ...
Mar 1, 2017
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Researchers at Okayama University report in the journal Matters, a potential third factor in the pathogenesis of Lafora disease. In addition to gene mutations, chemical modification of the enzyme Laforin induced by nitrosative ...
Feb 27, 2017
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The most common genetic cause of the brain diseases frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) is a mutation in the C9orf72 gene. Researchers from VIB and UAntwerp, headed by Prof. Christine Van ...
Feb 14, 2017
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Researchers at Uppsala University have identified gene mutations that are associated with the spread of metastases in colorectal cancer. The findings that have recently been published in the journal Cancer Research could ...
Jan 27, 2017
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Some diseases are untreatable because we lack a model system to fully understand symptoms or test possible drugs. This is the case of mitochondrial disease, a rare condition caused by defects in the "cellular powerhouse." ...
Jan 26, 2017
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A new study provides some of the first links between relatively common mutations in the blood cells of elderly humans and atherosclerosis.
Jan 19, 2017
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Scientists at the Center for Regenerative Medicine (CReM) at Boston Medical Center (BMC) and Boston University School of Medicine (BUSM) are creating an induced pluripotent stem cell (iPSC)-based research library that opens ...
Jan 19, 2017
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Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer's disease. Knowing the shape of the molecule—and how that shape may be ...
Dec 20, 2016
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