Medical research

Gene-edited disease monkeys cloned in China

The first cohort of five gene-edited monkey clones made from fibroblasts of a monkey with disease phenotypes were born recently at the Institute of Neuroscience (ION) of the Chinese Academy of Sciences (CAS) in Shanghai. ...

Diseases, Conditions, Syndromes

'GOLD' criteria may misdiagnosis normal phenotypes

(HealthDay)—The Global Lung Initiative (GLI)-defined normal spirometry includes adjusted mean values in the normal range for multiple phenotypes, even when classified as respiratory impairment by Global Initiative for Chronic ...

Medical research

Study explores in vivo role of ubiquinone in mouse model

(HealthDay)—Ubiquinone (UQ) does not act as an antioxidant in vivo, and partial restoration of UQ levels and mitochondrial function can reverse severe disease phenotypes and shortened lifespan, according to an experimental ...

Diabetes

Genetic link to gestational diabetes

New Northwestern Medicine research on the genetics of diabetes could one day help women know their risk for developing gestational diabetes before they become pregnant—and lead to preventive measures to protect the health ...

Genetics

Candidate drug provides benefit in SMA animal models

In a new publication that appears in Human Molecular Genetics, the laboratory of Christine DiDonato, PhD reports on their pharmacological characterization of the drug RG3039, demonstrating that it can extend survival and ...

Health

Systematic screening of med adherence will ID barriers

(HealthDay)—Implementation of systematic monitoring for medication adherence will allow for identification of barriers to adherence and tailoring of interventions, according to a viewpoint piece published in the May 22/29 ...

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