Oncology & Cancer

Scientists alter 3-D genome using 'small molecules'

Researchers have discovered that the spatial organization of the genome can be altered using small molecule compounds which are considered as promising anti-cancer drugs. This work opens up the prospect of developing a new ...

Immunology

Shellfish allergies: can they be treated?

Seafood platters? Bouillabaisse? Arroz de Marisco? Seafood paella? Oysters Rockefeller? Lobster Thermidor? Dining out with friends, a romantic meal, celebrating Christmas or a holiday on a wind-swept coast with these seafood ...

Oncology & Cancer

Are all cancer cells the same?

Take two cancer cells and compare their genomes. Surprisingly, they can be quite different. This genetic variation is one of the hallmarks of cancer, and one reason why treating cancer is so hard.

Oncology & Cancer

Rethinking existing method opens new doors for cancer diagnostics

All diseases have a genetic component. Advances in understanding the genetic mechanisms behind these disease enables the development of early diagnostic tests, new treatments, or interventions to prevent disease onset or ...

Oncology & Cancer

Trading in the scalpel for a sharper blade

Losing a breast or a lung to cancer leaves a scar, both physical and emotional. But even a biopsy to determine if a tumor is cancerous, or to track a tumor's response to drugs, brings short-term pain and can miss signs of ...

Genetics

Mapping the 'dark matter' of human DNA

Researchers from ERIBA, Radboud UMC, XJTU, Saarland University, CWI and UMC Utrecht have made a big step towards a better understanding of the human genome. By identifying large DNA variants in 250 Dutch families, the researchers ...

Medical research

Researchers discover a new player in tumor suppression and aging

A study conducted by the Spanish National Cancer Research Centre´s (CNIO) Genomic Instability Group, led by Óscar Fernández-Capetillo, describes for the first time in mammals, the role played by the SMC5/6 protein complex ...

Genetics

Genome editing in mitochondria prevents inheritance of diseases

Mitochondrial diseases are maternally inherited genetic disorders that cause a wide spectrum of debilitating conditions and which currently have no cure. In a study published April 23 in the journal Cell, Salk Institute researchers ...

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