In a new paper published today in Nature, researchers at the Francis Crick Institute have outlined the structure and function of a protein complex that is required to repair damaged DNA and protect against cancer.
Jun 21, 2023
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A new family of DNA elements which control the activation of certain genes known to cause a rare disease known as MSL3 syndrome in children has been identified.
Jun 12, 2023
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Researchers from Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Medical University of Lodz have found a way to detect increased cancer risk associated with BRCA1 and BRCA2 mutations without genetic sequencing, ...
Jun 8, 2023
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Australian cancer researchers have made an important new connection between a person's cancer risk and the functions of circular RNAs, a recently discovered family of genetic fragments present within our cells.
Jun 8, 2023
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A cleft lip or palate arises from the combined effects of genes and inflammatory risk factors experienced during pregnancy, such as smoking or infections, finds a new study led by UCL researchers.
May 24, 2023
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A team of researchers at the Broad Institute of MIT and Harvard has developed a new approach to next-generation sequencing that detects genetic mutations within single molecules of DNA.
Apr 28, 2023
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Routine diagnostic analyses of mutations in cell-free DNA in patients with metastatic prostate cancer are now possible for the first time in Sweden. The test has been developed by researchers at Karolinska Institutet, and ...
Apr 27, 2023
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Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled—a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease. It is ...
Apr 13, 2023
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CU Boulder researchers have discovered a protein's crucial role in helping breast and ovarian tumors survive and thrive and have found that suppressing that protein kills cancer cells without harming healthy ones.
Apr 13, 2023
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Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive. To identify previously unknown genes ...
Apr 4, 2023
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