Genetics

DNA discovery could advance degenerative disease treatments

New research on the structure and dynamics of a branched form of DNA called a three-way junction could lead to more effectively targeted treatments for degenerative disorders like Huntington's Disease, scientists say.

Oncology & Cancer

A more sensitive way to detect circulating tumor cells

Breast cancer is the most frequently diagnosed cancer in women, and metastasis from the breast to other areas of the body is the leading cause of death in these patients. Detecting circulating tumor cells (CTCs) in the bloodstream ...

Diseases, Conditions, Syndromes

CRISPR-based malaria testing on the fly

To achieve the goal of eradicating malaria set by the World Health Organization (WHO)'s Global Malaria Control Programme, it is critical that all local transmission of malaria parasites in defined geographic areas is eliminated. ...

Genetics

New mutations accumulate in reproductive cells of older mice

Older mice have more new mutations—changes in DNA sequence that occur in the individual rather than being inherited from a parent—than younger mice in the genomes of their mitochondria, according to researchers at Penn ...

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