For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in ...
Jun 30, 2020
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Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma—a malignant brain tumor with a very poor prognosis. The ...
Jun 9, 2020
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260
By combining RNA sequencing, bioinformatics and mathematical modeling, University of California San Diego School of Medicine and Moores Cancer Center researchers identified a sudden transcriptomic switch that turns healthy ...
Dec 17, 2019
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89
New research by Yale University scientists reports the discovery of "hyperhotspots" in the human genome, locations that are up to 170-times more sensitive to ultraviolet radiation (UV) from sunlight compared to the genome ...
Nov 14, 2019
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160
A new, multicenter study led by Fred Hutchinson Cancer Research Center and Memorial Sloan Kettering Cancer Center determined how a single mutation in splicing factor 3b subunit 1 (SF3B1), the most frequently mutated splicing ...
Oct 9, 2019
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Babies born vaginally have different gut bacteria—their microbiome—than those delivered by Caesarean, research has shown. Scientists from the Wellcome Sanger Institute, UCL, the University of Birmingham and their collaborators ...
Sep 18, 2019
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New findings suggest that women with specific DNA characteristics in certain areas of the genome may live longer if they take aspirin before they are diagnosed with breast cancer. Published early online in CANCER, a peer-reviewed ...
Aug 12, 2019
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394
A seldom-studied class of immune cells may reduce the friendly fire that drives autoimmune disease, according to a new study by researchers at the Stanford University School of Medicine. Stimulating these protective cells ...
Aug 7, 2019
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182
A new study published in Cell Reports found that a transcription factor called Slug serves as "command central" for determining breast stem cell health, regulating both stem cell activity and repair of DNA damage. The research ...
Jul 16, 2019
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Researchers at Rady Children's Institute for Genomic Medicine (RCIGM) have utilized a machine-learning process and clinical natural language processing (CNLP) to diagnose rare genetic diseases in record time. This new method ...
Apr 24, 2019
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