Researchers at Tel Aviv University warn that CRISPR therapeutics can damage the genome. They caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover ...
Jul 25, 2022
0
464
Rampant inflammation has long been linked to cancer but exactly how it pushes healthy cells to transform into malignant ones has remained a mystery.
Jun 7, 2022
0
907
When a non-metastatic brain tumor—a meningioma—recurs after surgery and radiation treatment, a patient is out of options. No drugs are approved for these aggressive tumors, which occur in up to 20% of cases and can lead ...
May 9, 2022
0
615
Inside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mutations—may build up at a faster rate. A new study by investigators from Brigham and ...
Apr 20, 2022
0
54
Researchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow it down—a finding that could provide new drug targets to resist Alzheimer's disease and other degenerative ...
Apr 5, 2022
0
217
A new DNA test, developed by researchers at the Garvan Institute of Medical Research in Sydney and collaborators from Australia, UK and Israel, has been shown to identify a range of hard-to-diagnose neurological and neuromuscular ...
Mar 4, 2022
0
2184
The stretches of DNA that differ from person to person, called variants, are a major part of what makes us unique, but they can also put us at greater risk of disease. Although we can currently spell out between 80% and 90% ...
Feb 7, 2022
0
18
A new analysis has uncovered a potential link between higher prostate cancer risk and genetic variants associated with higher bloodstream levels of the cholesterol-transporting molecule lipoprotein A. Anna Ioannidou of Imperial ...
Jan 27, 2022
0
59
Different diseases have different methods for testing if a person has the disease or not. immuneML, a new open source machine learning platform, can potentially look for a lot of diseases in just one blood sample.
Jan 26, 2022
0
44
Imagine getting a positive result on a genetic test. The doctor tells you that you have a "pathogenic genetic variant," or a DNA sequence that is known to raise the chances for getting a disease like breast cancer or diabetes. ...
Jan 25, 2022
0
30
