Human genomes vary quite a bit from individual to individual. These differences include single nucleotide changes, or "spelling mistakes" in the DNA sequence, but even more variation comes from structural variants, which ...
Apr 16, 2019
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In a pioneering study, scientists at A*STAR's Genome Institute of Singapore (GIS) have developed new machine learning computer models, a type of artificial intelligence (AI), to accurately pinpoint cancer mutations. They ...
Apr 19, 2018
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Scientists at the Francis Crick Institute have described the molecular structure of a key tumour suppressor protein and provided insights into its role in cells.
Jan 11, 2017
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Scientists from The University of Western Australia have identified how using cannabis can alter a person's DNA structure, causing mutations which can expose them to serious illnesses, and be passed on to their children and ...
May 24, 2016
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During embryonic life, the emergence of body limbs is orchestrated by a family of architect genes, which are themselves regulated by two DNA structures. While the first presides over the construction of the arm, the other ...
May 19, 2016
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Scientists at the University of Dundee have discovered that "molecular scissors" that repair damaged and abnormal DNA are critical for keeping cancers at bay.
Feb 2, 2016
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DNA damage can lead to gene inactivation or deregulation and cause various diseases such as cancer; however, many DNA repair mechanisms allow cells to survive against such damage. A study lead by Antoine Simoneau of the laboratory ...
Jan 28, 2016
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Carrying around a spare tire is a good thing—you never know when you'll get a flat. Turns out we're all carrying around "spare tires" in our genomes, too. Today, in ACS Central Science, researchers report that an extra ...
Jul 6, 2015
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Almost 2,500 women of child-bearing age in the UK are at risk of transmitting mitochondrial disease to their children, according to the most recent estimates published today in the New England Journal of Medicine.
Jan 28, 2015
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Researchers at the University of Louisville's James Graham Brown Cancer Center have identified for the first time mutations that destabilize a DNA structure that turns a gene off. These mutations occur at four specific sites ...
Dec 22, 2014
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