Psychology & Psychiatry

Low dopamine levels during withdrawal promote relapse to smoking

Mark Twain said, "Giving up smoking is the easiest thing in the world. I know because I've done it thousands of times." Many smokers would agree that it's difficult to stay away from cigarettes. A new study in Biological ...

Addiction

One step closer to a new drug for alcohol dependence

Researchers at Karolinska Institutet and the Sahlgrenska Academy in Sweden might be one step closer to finding an effective drug for alcohol dependence. In two separate studies, they show that the dopamine stabilizer OSU6162 ...

Psychology & Psychiatry

Novelty speeds up learning thanks to dopamine activation

Brain scientists led by Sebastian Haesler (NERF, empowered by IMEC, KU Leuven and VIB) have identified a causal mechanism of how novel stimuli promote learning. Novelty directly activates the dopamine system, which is responsible ...

Neuroscience

Synaptic connectivity of a novel cell population in the striatum

A new study from the Department of Neuroscience at Karolinska Institutet characterizes a novel neuronal population in the basal ganglia, responsible for the interaction between two types of neurotransmitters, GABA and acetylcholine. ...

Addiction

Potential new drug for alcohol dependence

(Medical Xpress) -- Research from Karolinska Institutet has identified a monoamine stabiliser as a potential new drug for the treatment of alcohol dependence. Tested on rats, whose reward system is gradually blunted by long-term ...

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