Neuroscience

Dopamine's yin-yang personality: It's an upper and a downer

For decades, psychologists have viewed the neurotransmitter dopamine as a double-edged sword: released in the brain as a reward to train us to seek out pleasurable experiences, but also a "drug" the constant pursuit of which ...

Neuroscience

Monkey gaze study shows dopamine's role in response inhibition

University of Tsukuba researchers report the importance of the brain's dopaminergic system for inhibiting already-planned actions. They trained monkeys to redirect their gaze toward targets presented on a screen, apart from ...

Neuroscience

Moving the motivation meter

Two novel drugs kickstart motivation in rats suffering from apathy and a lack of oomph, UConn researchers reported at the Society for Neuroscience conference in San Diego on Nov. 5.

Neuroscience

Dopamine primes the brain for enhanced vigilance

Imagine a herd of deer grazing in the forest. Suddenly, a twig snaps nearby, and they look up from the grass. The thought of food is forgotten, and the animals are primed to respond to any threat that might appear.

Neuroscience

Is foraging behaviour regulated the same way in humans and worms?

How does our nervous system motivate us to get off the sofa and walk to the fridge, or even to the supermarket, to get food? A research team led by Alexander Gottschalk from Goethe University investigated this using the threadworm ...

Neuroscience

Dopamine drives early addiction to heroin

Scientists have made a major advance in untangling the brain circuits that lead to the powerful addictive effects of heroin, a study in the open-access journal eLife reports.

Parkinson's & Movement disorders

Gene therapy for Parkinson's symptoms shows promise

(HealthDay)—A new gene therapy might help improve motor symptoms in people with Parkinson's disease who aren't responding to other therapies, an early study has found.

Neuroscience

Just a few drinks can change how memories are formed

One of the many challenges with battling alcohol addiction and other substance abuse disorders is the risk of relapse, even after progress toward recovery. Even pesky fruit flies have a hankering for alcohol, and because ...

Parkinson's & Movement disorders

Innovative gene therapy trial for Parkinson's disease

A trial for a new gene therapy, known as AXO-Lenti-PD, aimed at improving the supply of dopamine in the brains of people with Parkinson's disease has been launched by researchers at UCL and University College London Hospitals ...

Neuroscience

Researchers uncover new target of alcohol in the brain

When alcohol enters the brain, it causes neurons in a specialized region called the ventral tegmental area, or VTA—also known as the "pleasure center"—to release dopamine, a neurotransmitter that produces those feel-good ...

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