According to new research conducted in mice by Whitehead Institute scientists, surgery in breast cancer patients, which while often curative, may trigger a systemic immunosuppressive response, allowing the outgrowth of dormant ...
Apr 12, 2018
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Although men with prostate cancer usually respond to standard treatment with hormone therapy or chemotherapy, many will eventually experience progression or recurrence despite treatment—particularly those with high-risk ...
Dec 22, 2017
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A study by scientists at the University of Arizona and the University of Pittsburgh may hold the key to targeting dormant—or inactive —cancer cells, which are resistant to chemotherapy and other treatments. The results ...
Sep 26, 2017
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Even before tumors develop, breast cancer cells with a few defined molecular alterations can spread to organs, remain quiet for long periods of time, and then awaken to form aggressive, deadly breast cancer metastasis, says ...
Dec 14, 2016
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A study published today by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine describes that certain proteins playing a role in cancer progression and metastasis are ...
Oct 6, 2016
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Scientists at the Duke Cancer Institute have identified a molecular key that breast cancer cells use to invade bone marrow in mice, where they may be protected from chemotherapy or hormonal therapies that could otherwise ...
May 25, 2016
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Intermittent dosing with rapamycin selectively breaks the cascade of inflammatory events that follow cellular senescence, a phenomena in which cells cease to divide in response to DNA damaging agents, including many chemotherapies. ...
Jul 6, 2015
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Tumor recurrence following a period of remission is the main cause of death in cancer. The ability of cancer cells to remain dormant during and following therapy, only to be reactivated at a later time, frequently with greater ...
Mar 3, 2015
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Scientists have discovered how breast cancer cells can "hibernate" to avoid treatment and "wake up" years later—causing a relapse that is more difficult to treat.
Mar 26, 2024
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Just as she hoped to start a family, Denise Murray was diagnosed with an aggressive form of breast cancer. Thirty years old and newly married, she felt it was too risky to consider pregnancy if she might not live to raise ...
Nov 7, 2023
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