Massachusetts General Hospital (MGH) investigators have identified two compounds that appear, in cellular and animal models, to block the cardiac damage caused by the important chemotherapy drug doxorubicin. Their report ...
Dec 10, 2014
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Doxorubicin, a 50-year-old chemotherapy drug still in widespread use against a variety of cancers, has long been known to destroy heart tissue, as well as tumors, in some patients.
Oct 28, 2012
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A team led by Dr. Lorrie Kirshenbaum from the Rady Faculty of Health Sciences and St. Boniface Hospital Research has identified a protein called TRAF2 that stops functioning in cancer patients taking the chemotherapy drug ...
Nov 7, 2022
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A new treatment combining shock waves with nanoparticles can successfully treat tumours that are difficult to target using conventional chemotherapy. This is the first time this combined therapy has been tested in live animals. ...
May 10, 2017
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(HealthDay)—Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors, with a decreased risk for daunorubicin versus doxorubicin, according to a study recently published in JAMA Oncology.
Mar 1, 2019
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In the human gut, good bacteria make great neighbors.
May 26, 2021
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(HealthDay) -- For patients with operable breast cancer, peripheral neuropathy due to adjuvant taxane therapy does not correlate with improved outcomes, according to research published online July 30 in the Journal of Clinical ...
Aug 2, 2012
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Blocking a protein in the heart that is produced under stressful conditions could be a strategy to prevent cardiac damage that results from chemotherapy, a new study suggests.
May 21, 2012
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Chemotherapy is one of the main therapeutic modalities for cancer patients. Chemotherapeutic drugs destroy cancer cells in the body, but patients frequently face side effects since the drugs do not selectively target cancer ...
Aug 31, 2023
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(HealthDay)—The first generic version of the cancer drug Doxil (doxorubicin hydrochloride liposome injection) has been approved by the U.S. Food and Drug Administration, which says the action should help relieve shortages ...
Feb 4, 2013
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