For people with cancer, chemotherapy saves lives, but for some patients, the treatment comes with a side effect—heart damage. Screening cancer drugs for cardiotoxicity has been an ongoing challenge, as heart cells don't ...
Apr 20, 2023
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A team led by Dr. Lorrie Kirshenbaum from the Rady Faculty of Health Sciences and St. Boniface Hospital Research has identified a protein called TRAF2 that stops functioning in cancer patients taking the chemotherapy drug ...
Nov 7, 2022
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A team of investigators has discovered a genomic variant that may help clinicians predict which patients will experience cardiotoxicity from a widely used chemotherapy drug, according to a Northwestern Medicine study published ...
Jan 4, 2022
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Unlike conventional cancer drugs that attack and kill cancer cells directly, anti-cancer immunotherapy, which kills cancer cells by strengthening the body's immunity, is a novel type of cancer treatment currently attracting ...
Jun 28, 2021
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Many cancers can be successfully treated, but treatment itself often comes with risks as well. Cancer therapy that uses anthracyclines—a class of commonly used chemotherapy drugs—has been associated with heart damage ...
Apr 9, 2020
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Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice. In the preclinical study, the team found that ...
Sep 25, 2019
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(HealthDay)—Taxane plus platinum regimens may be a reasonable alternative to doxorubicin plus cisplatin as postoperative adjuvant chemotherapy for endometrial cancer that carries a high risk for progression, according to ...
Mar 27, 2019
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(HealthDay)—Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors, with a decreased risk for daunorubicin versus doxorubicin, according to a study recently published in JAMA Oncology.
Mar 1, 2019
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A new study by Washington State University researchers suggests that a protein called CDK2 plays a critical role in heart damage caused by doxorubicin, a commonly used chemotherapy drug.
Nov 7, 2018
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Doxorubicin is a chemotherapy drug widely used in ovarian, bladder, lung, thyroid and stomach cancers, but it carries a harmful side effect. The drug causes a dose-dependent heart toxicity that can lead to congestive heart ...
Aug 6, 2018
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