Medications

Medications underused in treating opioid addiction, expert says

Though research shows that medication-assisted treatment can help people who are addicted to opioids, the three drugs approved by the Food and Drug Administration (FDA) are underused, according to a review of current medical ...

Addiction

Researcher discovers gene mutation that contributes to addiction

In the field of addiction research, one question looms large: Why do some people face a higher risk than others for alcoholism and drug abuse? A researcher at the OU College of Medicine, William R. Lovallo, Ph.D., recently ...

Medications

OxyContin maker Purdue agrees to provide research data

The maker of the powerful painkiller OxyContin has agreed to provide access to propriety research and other data to researchers at Oklahoma State University to help them find causes and treatments for drug addiction.

Medications

Family influence key in spread of opioid use

Introducing an opioid painkiller into a home can double the chances someone else living in the home seeks out the addictive drugs on his or her own, according to a new paper from two UC Berkeley researchers.

Addiction

Blocking dopamine weakens effects of cocaine

Blocking dopamine receptors in different regions of the amygdala reduces drug seeking and taking behavior with varying longevity, according to research in rats published in eNeuro.

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Drug addiction

Drug addiction is a pathological condition. The disorder of addiction involves the progression of acute drug use to the development of drug-seeking behavior, the vulnerability to relapse, and the decreased, slowed ability to respond to naturally rewarding stimuli. The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) has categorized three stages of addiction: preoccupation/anticipation, binge/intoxication, and withdrawal/negative affect. These stages are characterized, respectively, everywhere by constant cravings and preoccupation with obtaining the substance; using more of the substance than necessary to experience the intoxicating effects; and experiencing tolerance, withdrawal symptoms, and decreased motivation for normal life activities. By the American Society of Addiction Medicine definition, drug addiction differs from drug dependence and drug tolerance.

It is, both among scientists and other writers, quite usual to allow the concept of drug addiction to include persons who are not drug abusers according to the definition of the American Society of Addiction Medicine. The term drug addiction is then used as a category which may include the same persons who under the DSM-IV can be given the diagnosis of substance dependence or substance abuse. (See also DSM-IV Codes)

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